Home / Blog February 01, 2024

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Should I Use Gabapentin For Sleep?

In this blog, we discuss how Gabapentin can improve sleep quality. We start by explaining what Gabapentin is and its historical application for sleep problems. We then delve into the connection between Gabapentin and anxiety and provide general tips on sleep hygiene.

gabapentin for sleep


Gabapentin is a medication that calms the nervous system.

It is often used to treat seizures, such as in the case of epilepsy.

Due to its side effect of drowsiness, Gabapentin is used off-label for sleep disorders. 

Did you know?
In case of an overdose, there is no specific antidote for Gabapentin, emphasizing the importance of caution and prescription usage only.

If sleep troubles or conditions like Restless Legs Syndrome (RLS) keep you up at night, you might have considered trying Gabapentin as a solution. In this blog, we unravel Gabapentin’s role in improving sleep, its potential side effects, and alternative strategies for improving your sleep quality. Let’s begin by understanding what exactly this medication is!

What Is Gabapentin?

Gabapentin is a prescription medicine commonly used for pain and seizures caused by epilepsy. It soothes your nerves by reducing sensitivity to pain. Usually taken as a pill, it’s essential to stick to the prescribed dosage and schedule to avoid any complications.

Gabapentin has been marketed under different brand names, such as Neurontin, Gralise, and Horizant (for the extended-release version). So, let’s look at what these medications do in your body.

How Exactly Does Gabapentin Work?

Gabapentin affects the activity of certain signals in your body’s nervous system. It belongs to a class of medicines known as anticonvulsants, also referred to as antiseizure medications. However, Gabapentin’s mechanism of action also proves beneficial for conditions involving nerve-related pain as well as anxiety.

Gabapentin typically mirrors gamma-aminobutyric acid (GABA), a chemical messenger (neurotransmitter) in the brain. It plays a crucial role in calming nerve activity by inhibiting or reducing the firing of neurons. In simpler terms, GABA acts like a "brake" in the brain, helping to prevent excessive neural activity, which can lead to anxiety, stress, and overstimulation.

This calming effect can reduce how you perceive pain and contribute to its role in potentially improving sleep. In the next section, we look at whether or not this is Gabapentin’s intended use.

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What Has Gabapentin Been Approved For?

Gabapentin has been approved by the U.S. Food and Drug Administration (FDA) for various medical uses, including:

Epilepsy: The FDA approved Gabapentin (and its other names, like Neurontin) as an antiseizure medication. This means that it is primarily prescribed for managing symptoms associated with epilepsy.

Postherpetic Neuralgia: It is approved for the treatment of postherpetic neuralgia. This is persistent pain that occurs after a person has had shingles, which is a viral infection characterized by a painful rash.

Restless Legs Syndrome (RLS): According to the National Institutes of Health (NIH), Gabapentin enacarbil, a prodrug of gabapentin, has received approval for the treatment of moderate-to-severe primary Restless Legs Syndrome. A prodrug is simply a medication or compound that is inactive or less active when you take it, but it gets converted into an active form inside your body. It's like a "silent" or "masked" version of a drug that only becomes effective after undergoing a specific chemical change within your body.

While these are the FDA-approved uses, healthcare providers may sometimes prescribe gabapentin off-label for conditions not officially listed on the label, such as certain types of pain, anxiety disorders, or sleep disturbances. Let’s look at why some medical professionals prescribe Gabapentin for sleep.

While it is not FDA-approved for treating sleep disorders other than RLS, Gabapentin is occasionally used off-label to address sleep-related issues. The impact of Gabapentin on sleep quality varies from person to person, but here are the common ways in which Gabapentin can influence sleep:

1. Pain Reduction: Gabapentin is known for its ability to reduce nerve pain. If pain is contributing to sleep disturbances, the medication may improve sleep quality by alleviating discomfort.

2. Anxiolytic Effects: Some people find that Gabapentin has mild anxiolytic (anxiety-reducing) effects. If anxiety is a factor affecting sleep, Gabapentin may indirectly contribute to falling asleep quicker and staying asleep for longer.

3. Sedation: One common side effect of Gabapentin is drowsiness. For some people, this sedating effect can be beneficial to restful sleep

While some people may experience improved sleep quality with Gabapentin, others might not. Additionally, there can be side effects and considerations that should be discussed with a healthcare provider before using Gabapentin for sleep. Let’s discuss some potential side effects in the next section.

Side Effects Of Using Gabapentin For Sleep

Like any medication, Gabapentin may have side effects. Common side effects can include:

1. Drowsiness or Fatigue: Gabapentin can cause drowsiness, which might be beneficial if taken before bedtime but could be problematic during the day.

2. Dizziness: Some people may experience dizziness or lightheadedness, especially when standing up quickly.

3. Coordination Problems: Gabapentin may affect coordination and balance in some individuals.

4. Peripheral Edema: This is swelling in the extremities, such as the hands or feet, which can occur while taking Gabapentin on or off-label.

5. Weight Gain: Some individuals may experience weight gain while taking gabapentin

6. Nausea and Vomiting: These gastrointestinal symptoms can occur, although they are less common.

7. Visual Disturbances: Some people may experience blurred or double vision, which could be dangerous for activities such as driving.

8. Insomnia: Paradoxically, while some people may feel drowsy, others might experience difficulty sleeping.

Individual responses to medication can vary, and not everyone will experience these side effects. If you start taking Gabapentin and experience side effects that are interfering with your work and daily activities, seek professional medical advice on how to proceed.

For example, some people have reported that gabapentin actually makes them struggle with sleeping at night. In the next section, we discuss how Gabapentin may interfere with your sleep quality.

Can Gabapentin Cause Sleep Disturbances?

Gabapentin may have several effects on sleep. While some people find that it helps improve their sleep by reducing pain or addressing other underlying issues, others experience sleep disturbances as a side effect. Here are a few ways Gabapentin might impact sleep:

1. Alertness: In some cases, medications can have paradoxical effects, meaning they produce effects opposite to what you expect. While Gabapentin is often associated with drowsiness, some people may experience increased alertness, which may also lead to insomnia.

2. Daytime Sleepiness: Excessive daytime sleepiness can occur in some people taking Gabapentin, impacting their overall sleep-wake cycle and ability to maintain productive work.

3. Sleep Quality: Some may find an improvement in sleep due to reduced pain or anxiety, while others might experience disruptions.

If you’re using Gabapentin for sleep and notice any sleep disturbances or concerns, it's crucial to communicate with your healthcare provider. This is especially true if you’re using it for off-label purposes, one of which is reducing anxiety. Let’s look at what the research says on the relationship between Gabapentin and anxiety.

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Can I Use Gabapentin For Anxiety?

The use of Gabapentin for anxiety is also considered off-label, as the medication is primarily prescribed for conditions like epilepsy and neuropathic pain. If your healthcare provider suggests using Gabapentin for its anxiety-reducing effects, they will determine the appropriate dosage based on your individual health needs and response to the medication.

One case study by the National Institutes of Health (NIH) reports a decrease in symptoms of Generalized Anxiety Disorder (GAD) on prescribing Gabapentin for a patient. However, due to a lack of randomized controlled trials, there is no sure way of recommending Gabapentin for anxiety.

Because of this, the prescribed dosage for Gabapentin can vary widely depending on the individual and the specific condition being treated. Typically, a starting dose for anxiety might be in the range of 100 to 300 milligrams taken one to three times per day. However, individual responses can vary, and your doctor will tailor the dosage to your specific situation.

It's crucial to follow your healthcare provider's instructions carefully and not to self-adjust the dosage without consulting them. If anxiety is interfering with your ability to fall and stay asleep, there are some other changes you can make in your lifestyle to improve the quality of your sleep and the need for medication can be minimized.

Let’s take a look at these in the next section.

How To Sleep Better Without Medication

Improving sleep without medication involves adopting healthy sleep habits. Here are some drug-free tips for improving your sleep hygiene:

1. Consistent Sleep Schedule: Establishing a consistent sleep schedule involves going to bed and waking up at the same time every day, even on weekends. This routine helps regulate your body's internal clock, enhancing the overall quality of your sleep. The body thrives on routine, and a consistent sleep schedule reinforces natural circadian rhythms.

2. Create a Relaxing Bedtime Routine: Developing a calming pre-sleep ritual signals to your body that it's time to wind down. This can include activities like reading a book, taking a warm bath, or practicing relaxation techniques. These activities help shift your mind from the day's stressors to a more serene state conducive to sleep

3. Limit Exposure to Screens: Reduce exposure to screens, such as phones, tablets, computers, and TVs, at least an hour before bedtime. The blue light emitted from screens can interfere with melatonin production, the hormone responsible for regulating sleep. Opt for activities that don't involve screens to promote a more natural transition to sleep.

4. Use A Weighted Blanket: Weighted blankets provide a comforting and calming effect for many people. The gentle full-body weight promotes Deep Touch Pressure (DTP), which has been linked to increased melatonin (sleep hormone) production. This is why knitted weighted blankets like our Cotton Napper can be helpful if you struggle with sleep disorders like RLS or Sleep Apnea. The gentle pressure of a weighted blanket can create a sense of security, aiding in relaxation and better sleep.

5. Comfortable Sleep Environment: Create a sleep-conducive environment in your bedroom. Keep the room cool, dark, and quiet. Investing in a comfortable mattress and pillows is essential for physical comfort, supporting proper spinal alignment, and reducing disruptions.

6. Regular Exercise: Engage in regular physical activity, but avoid intense workouts close to bedtime. Exercise helps regulate sleep patterns, reduces stress, and promotes overall well-being. Establishing a routine that includes physical activity can contribute to better sleep quality.

7. Watch Your Diet: Be mindful of your diet, especially close to bedtime. Avoid large meals, caffeine, and nicotine in the evening. If you're hungry before bed, opt for a light snack. A well-balanced diet contributes to overall health, positively impacting your sleep.

8. Mindfulness and Relaxation Techniques: Practice relaxation techniques like deep breathing, meditation, or progressive muscle relaxation to calm the mind. These techniques can alleviate stress and anxiety, creating a mental state conducive to falling asleep peacefully

9. Limit Naps: If you need to take an afternoon nap, keep it short (20-30 minutes) and avoid napping late in the day. While naps can be refreshing, prolonged or late-day naps may interfere with your ability to fall asleep at night.

10. Manage Stress: Develop healthy strategies to manage stress, such as journaling, talking to a friend, or seeking professional support if needed. Chronic stress can contribute to sleep disturbances, so finding effective stress management techniques is crucial for promoting better sleep.

11. Sunlight Exposure: Get exposure to natural sunlight during the day, especially in the morning. Natural light exposure helps regulate your body's internal clock, reinforcing a wakeful state during the day and promoting better sleep at night.

12. Limit Liquid Intake Before Bed: Minimize the consumption of liquids close to bedtime to reduce the likelihood of waking up to use the bathroom. This practice can contribute to uninterrupted sleep throughout the night.

If you continue to experience sleep difficulties despite adopting these strategies, it's essential to consult with a healthcare professional to rule out any underlying sleep disorders or health issues. So in the next section, we share some things to look out for to know when you should seek medical attention for any sleep disturbances you’re experiencing.

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When To See A Doctor

If you're experiencing persistent sleep disturbances, it's a good idea to consult with a healthcare professional. Here are some signs that indicate it's time to see a doctor about your sleep issues:

  • Chronic insomnia
  • Excessive daytime sleepiness
  • Loud snoring or pauses in breathing
  • Restless legs syndrome (RLS)
  • Frequent nightmares or night sweats
  • Difficulty concentrating or memory issues
  • Changes in sleep patterns
  • Persistent fatigue or irritability
  • Unexplained weight gain or loss
  • Ongoing stress or anxiety 

Poor sleep can be a symptom of various underlying health conditions, including sleep disorders, mental health concerns, or physical ailments. Consulting with a healthcare provider can help identify the root cause and guide appropriate treatment

Before your appointment, consider keeping a sleep diary detailing your sleep patterns, daily activities, and any medications or substances you consume. This information can assist your doctor in making an accurate diagnosis.


While Gabapentin has been used off-label for sleep disturbances, you should not use it without consulting your doctor. It is important to consult with a healthcare provider for personalized and professional advice on the sleep disturbances you’re experiencing.

Adopting healthy sleep habits, like maintaining a consistent schedule and creating a relaxing bedtime routine, can contribute to better sleep quality without the use of medication. If sleep issues persist or you experience sudden changes in your sleep patterns, it’s best to seek help from a doctor to identify and address underlying causes.